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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 903586Generated: October 26, 2026

Methyltryptamine → N-methyl-N-(4-methoxycarbonylbutyryl)-tryptamine

https://huagongshe.com/reaction/903586

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyltryptamineHCID 6088—
ReactantMethyl 4-chloroformylbutyrateHCID 73916—
ProductN-methyl-N-(4-methoxycarbonylbutyryl)-tryptamineHCID 2333648092.9%

Reaction Steps

10.3 g of N-methyl-tryptamine (i.e., 3-(2-methylaminoethyl)-indole) and 11.7 g of 4-methoxycarbonylbutyryl chloride were treated in the same manner as described in Example 1. 16.6 g of N-methyl-N-(4-methoxycarbonylbutyryl)-tryptamine (i.e., 3-[2-(N-methyl-4-methoxycarbonylbutanamido)ethyl]indole) were therby obtained. Yield: 92.8%

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04228168
Source datasetuspto-grants-1980_10
ORD IDord-a29b862b14cd4be6ab465ec07efaf95d
Source noteuspto-grants-1980_10