HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyltryptamine → 1,2,3,4-Tetrahydro-1-[3,3-bis(ethoxycarbonyl)-propyl]-2-methyl-beta-carboline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyltryptamine | HCID 6088 | — |
| Reactant | Diethyl (3-oxopropyl)malonate | HCID 88096 | — |
| Product | 1,2,3,4-Tetrahydro-1-[3,3-bis(ethoxycarbonyl)-propyl]-2-methyl-beta-carboline | HCID 23336481 | 55.2% |
Reaction Steps
1.78 g of N-methyl-tryptamine (i.e., 3-(2-methylaminoethyl)-indole) and 3.1 g of 4,4-bis(ethoxycarbonyl)-butanal were treated in the same manner as described in Example 21-(1). 2.1 g of 1,2,3,4-tetrahydro-1-[3,3-bis-(ethoxycarbonyl)propyl]-2-methyl-β-carboline were thereby obtained. Yield: 55.0%
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04228168 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-50ab92d2f9754825bd25d8207a0fbca9 |
| Source note | uspto-grants-1980_10 |