Methane → 1,2,3,4-Tetrahydro-1-(3-carboxypropyl)-2-methyl-beta-carboline hydrochloride

Participants

Reaction Conditions

Reaction Steps

25 ml of 5% hydrochloric acid were added to 1.08 g of 1,2,3,4-tetrahydro-1-[3,3-bis(ethoxycarbonyl)-propyl]-2-methyl-β-carboline, and the mixture was stirred at 80° C. for 5 hours. After the reaction was completed, the mixture was treated with activated charcoal powder and then condensed under reduced pressure. 930 mg of 1,2,3,4-tetrahydro-1-(3-carboxypropyl)-2-methyl-β-carboline hydrochloride were thereby obtained. Yield: 79.8%

Provenance & Evidence