5-Ethynylpyridin-2-amine → 5-[5-(3-Methyl-4-trifluoromethyl-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-pyridin-2-ylamine
Reaction equation
[C:26](#[CH:27])[c:28]1[cH:29][cH:30][c:31]([NH2:34])[n:32][cH:33]1.[I:1][c:2]1[cH:3][n:4][n:5]2[c:6]1[n:7][c:8](-[c:15]1[cH:16][c:17]([CH3:25])[c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]1)[cH:9][c:10]2[C:11]([F:12])([F:13])[F:14]>>[c:2]1([C:27]#[C:26][c:28]2[cH:29][cH:30][c:31]([NH2:34])[n:32][cH:33]2)[cH:3][n:4][n:5]2[c:6]1[n:7][c:8](-[c:15]1[cH:16][c:17]([CH3:25])[c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]1)[cH:9][c:10]2[C:11]([F:12])([F:13])[F:14]Participants
3
Sources & evidence
- ORD record
- ord-58c389763b5c45f4b34c02833538e159
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…