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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 903734Generated: October 30, 2026

1,3-Propanediamine → 2-(3-Aminopropylamino)pyrazine

https://huagongshe.com/reaction/903734

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-PropanediamineHCID 428—
ReactantChloropyrazineHCID 73277—
ReactantSodium ethoxideHCID 2723922—
SolventEthanolHCID 702—
Product2-(3-Aminopropylamino)pyrazineHCID 14397407—

Reaction Steps

Reacting 2-chloropyrazine with 1,3-diaminopropane in ethanol containing sodium ethoxide by the procedure of Example 89 gives 2-(3-aminopropylamino)-pyrazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04228291
Source datasetuspto-grants-1980_10
ORD IDord-6a8f21ac44c54cf69d93be831a099714
Source noteuspto-grants-1980_10