3-(4-Chlorobenzyl)-pyrrolylmethyl alcohol → 3-(4-Chlorobenzyl)-pyrrolylmethyl 3-(i-butoxy)-2,2-dimethylcyclopropanecarboxylate

HRID 903806Notes

Reaction equation

HRID 903806 reaction equation
[Cl:1][C:2]1[CH:15]=[CH:14][C:5]([CH2:6][C:7]2[CH:11]=[CH:10][NH:9][C:8]=2[CH2:12][OH:13])=[CH:4][CH:3]=1.[CH2:16]([O:20][CH:21]1[CH:23]([C:24](O)=[O:25])[C:22]1([CH3:28])[CH3:27])[CH:17]([CH3:19])[CH3:18]>>[CH2:16]([O:20][CH:21]1[CH:23]([C:24]([O:13][CH2:12][C:8]2[NH:9][CH:10]=[CH:11][C:7]=2[CH2:6][C:5]2[CH:4]=[CH:3][C:2]([Cl:1])=[CH:15][CH:14]=2)=[O:25])[C:22]1([CH3:28])[CH3:27])[CH:17]([CH3:19])[CH3:18]

Participants

3

Reactant 2

HCID 541605813-(4-Chlorobenzyl)-pyrrolylmethyl alcoholHCID 545425423-(i-Butoxy)-2,2-dimethylcyclopropanecarboxylic acid

Product 1

HCID 233351553-(4-Chlorobenzyl)-pyrrolylmethyl 3-(i-butoxy)-2,2-dimethylcyclopropanecarboxylate

Procedure

Using the above procedure, 3-(4-chlorobenzyl)-pyrrolylmethyl alcohol is reacted with 3-(i-butoxy)-2,2-dimethylcyclopropanecarboxylic acid to yield 3-(4-chlorobenzyl)-pyrrolylmethyl 3-(i-butoxy)-2,2-dimethylcyclopropanecarboxylate.

Sources & evidence

ORD record
ord-c8ff84fc24764f1c91fd9852b3db202d
Source dataset
uspto-grants-1980_10
Patent number
US04229352

Reaction notes

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