HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenolphthalein → (-)-alpha-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenolphthalein | HCID 4764 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | (-)-alpha-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid methyl ester hydrochloride | HCID 70585116 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (-)-alpha-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid methyl ester | HCID 53644499 | — |
Reaction Steps
(-)-α-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid methyl ester hydrochloride is dissolved in a minimum amount of methanol. To this solution is added methanolic potassium hydroxide until a basic reaction to phenolphthalein is observed. The potassium chloride which precipitates is removed and the solvent is removed under vacuum to give a quantitative yield of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04229363 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-677af14c299d4a7082676fdb10894b4a |
| Source note | uspto-grants-1980_10 |