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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 903833Generated: October 30, 2026

alpha-Amino-4-hydroxy-3-[(methylthio)methyl]benzeneacetic acid → (-)-alpha-Amino-4-hydroxy-3-[(methylsulfinyl)methyl]benzeneacetic acid

https://huagongshe.com/reaction/903833

Reaction equation

Participants

RoleNameHCIDCharge
Reactantalpha-Amino-4-hydroxy-3-[(methylthio)methyl]benzeneacetic acidHCID 23329760—
ReactantSodium periodateHCID 23667635—
Product(-)-alpha-Amino-4-hydroxy-3-[(methylsulfinyl)methyl]benzeneacetic acidHCID 23329781—

Reaction Steps

To an aqueous solution (500 ml) of α-amino-4-hydroxy-3-[(methylthio)methyl]benzeneacetic acid (1 mole) is added sodium metaperiodate (1 mole). The mixture is stirred at room temperature for 5 hours, it is filtered and the filtrate is lyophilyzed to give a quantitative yield of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04229363
Source datasetuspto-grants-1980_10
ORD IDord-e867d02bbde24d569052386c0cf34be9
Source noteuspto-grants-1980_10