Diazomethane → HCID 20528716, compound

HRID 903870Notes

Reaction equation

HRID 903870 reaction equation
[C:1]([C:4]1[CH:14]=[CH:13][CH:12]=[C:6]2[C:7]([NH:9][C:10](=[O:11])[C:5]=12)=[O:8])([OH:3])=[O:2].[N+](=[CH2:17])=[N-]>CCOCC>[CH3:17][O:2][C:1]([C:4]1[CH:14]=[CH:13][CH:12]=[C:6]2[C:7]([NH:9][C:10](=[O:11])[C:5]=12)=[O:8])=[O:3]

Participants

4

Reactant 2

HCID 9550DiazomethaneHCID 205447191,3-dioxo-2,3-dihydro-1H-isoindole-4-carboxylic acid

Product 1

HCID 20528716HCID 20528716, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

To a suspension of 3-carboxyphthalimide (10 g) in ether (50 ml), a solution of diazomethane in ether was added slowly until a faint yellow colouration persisted. Excess of diazomethane was destroyed with acetic acid and the reaction mixture was evaporated to yield the desired compound.

Workup

  1. customExcess of diazomethane was destroyed with acetic acid
  2. customthe reaction mixture was evaporated

Sources & evidence

ORD record
ord-d285e306ed5e42b19ca3f0039a71a8b7
Source dataset
uspto-grants-1980_10
Patent number
US04229443

Reaction notes

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