HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 903963Generated: October 30, 2026
Water → 3-(2-Methoxy-phenoxy)-3-phenyl-propylene
https://huagongshe.com/reaction/903963
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Benzene, 1-(chloromethyl)-3(or 4)-ethenyl- | HCID 11768772 | — |
| Reactant | HCID 70053666 | HCID 70053666 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-(2-Methoxy-phenoxy)-3-phenyl-propylene | HCID 23458392 | 99.2% |
Reaction Steps
To a solution of 5 g of guaiacol sodium salt in 60 ml of dimethylformamide, 1-phenylallyl-chloride (5.22 g) (J.C.S. 1959, p. 2720) was added under a nitrogen atmosphere. The whole was stirred for 4 hours at room temperature and for two hours at 50° C., poured into water and extracted with ethyl ether. After standard working up, followed by chromatographic separation, 3-(2-methoxy-phenoxy)-3-phenyl-propylene (8.1 g; 98%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04229449 |
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| Source dataset | uspto-grants-1980_10 |
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| ORD ID | ord-25e5f80f89de4d9899f4f41e4d5e1337 |
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| Source note | uspto-grants-1980_10 |
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