HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 131711929, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Glycine | HCID 750 | — |
| Reactant | L-Alanine | HCID 5950 | — |
| Reactant | L-Aspartic Acid | HCID 5960 | — |
| Reactant | L-Lysine | HCID 5962 | — |
| Reactant | L-Phenylalanine | HCID 6140 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | L-Glutamic Acid | HCID 33032 | — |
| Reactant | HCID 131711930 | HCID 131711930 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 131711929 | HCID 131711929 | — |
Reaction Steps
Using 500 mg of pGlu-Ala-Lys(Boc)-Ser-Gln-(D)-Phe-Gly-Ser-Asn-OBut and 15 ml of trifluoroacetic acid, the same procedure as Example 5-(VIII) is followed to prepare the above-identified compound. Yield 280 mg; [α]D24 -51.7°(c=0.2, water), Rf4 (Avicel)=0.35; amino acid analysis (hydrolyzed with HCl); Lys, 1.00(1); Asp, 0.70(1); Ser, 2.02(2); Glu, 2.03(2); Gly, 1.02(1); Ala, 0.77(1); Phe, 1.01(1); average recovery 84.5%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04229438 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-0392df895e4742a98d12b5aa559912c5 |
| Source note | uspto-grants-1980_10 |