HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 131711931, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Glycine | HCID 750 | — |
| Reactant | L-Alanine | HCID 5950 | — |
| Reactant | L-Aspartic Acid | HCID 5960 | — |
| Reactant | L-Lysine | HCID 5962 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | L-Glutamic Acid | HCID 33032 | — |
| Reactant | HCID 131711932 | HCID 131711932 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 131711931 | HCID 131711931 | — |
Reaction Steps
Using 550 mg of pGlu-Ala-Lys(Boc)-Ser-Gln-(D)-Ser-Gly-Ser-Asn-OBut and 20 ml of trifluoroacetic acid, the same procedure as Example 5-(VIII) is followed to prepare the above-indicated compound. Yield 320 mg; [α]D24 -56.3°(c=0.5, water); Rf4 (Avicel)=0.17; amino acid analysis (hydrolyzed with HCl); Lys, 1.10(1); Asp, 1.00(1); Ser, 3.02(3); Glu, 2.14(2); Gly, 1.10(1); Ala, 1.00(1); average recovery 87.0%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04229438 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-9820d08d7bb749a5bb4ebaf03882e92b |
| Source note | uspto-grants-1980_10 |