Dinitrofluorobenzene → HCID 13252395, compound

Participants

Reaction Steps

In a four necked flask, 1.43 g of 1,3-dimethyl-4-(2,4-dichlorobenzoyl)-5-hydroxypyrazole was dissolved in 15 ml of methyl ethyl ketone and 1.38 g of anhydrous potassium carbonate was added to the solution and 0.93 g of 2,4-dinitrophenylfluoride was added dropwise to the mixture under stirring. After the addition, the reaction was carried out for 3 hours under refluxing. The reaction mixture was filtered and methyl ethyl ketone was distilled off to obtain the precipitate of the reaction product. The precipitate was dissolved in methylene chloride and the solution was mixed with a saturated aqueous solution of sodium bicarbonate. The organic phase was separated and methylene chloride was distilled off to obtain the solid product. The solid product was washed with benzene to obtain 1.58 g of 1,3-dimethyl-4-(2,4-dichlorobenzoyl)-5-(2,4-dinitrophenoxy) pyrazole having a melting point of 190° to 192° C.

Provenance & Evidence