O-Cresol → HCID 23333445, compound

Participants

Reaction Conditions

Reaction Steps

108 g (1 mole) of orthocresol are added to a liter of nitrobenzene. The solution is cooled to 0° C. and 280 g (2.1 moles) of powdered aluminium chloride are added over a period of one hour (while stirring). While still stirring and at 0° C., 120.5 g (1 mole) of valeryl chloride are added over a period of one hour 30 minutes. The temperature of the solution is left for about 12 hours at this temperature. The solution is then poured into a mixture of 1 kg of ice and 500 ml of 37% hydrochloric acid. The mixture is stirred for one hour and the organic phase is decanted. It is whashed with 5 N hydrochloric acid and then with deionized water.

Provenance & Evidence