HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl chloroformate → HCID 23333519, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl chloroformate | HCID 10928 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 23333510 | HCID 23333510 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 23333519 | HCID 23333519 | — |
Reaction Steps
To 6.7 g (20 mmole) 4'-(hexafluoro-2-hydroxy-2-propyl)-methanesulfonanilide (prepared as in Example 1) in 100 ml acetonitrile, add 4.1 g (30 mmole) K2CO3 and 2.2 g (20 mmole) ethyl chloroformate. Stir 16 hours, filter and concentrate. Partition the residue between Et2O and 5% Na2CO3. Dry, concentrate and recrystallize first from Et2O-hexane and then from toluene to give the product; m.p. 108°-112° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04230635 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-75c75e6b349a43dd8f4b9ef496b2e04d |
| Source note | uspto-grants-1980_10 |