Hydrazinecarboxaldehyde → 6-Phenyl[1,2,4]triazolo[4,3-b]pyridazine

Participants

Reaction Steps

A 10 g. portion of 3-chloro-6-phenylpyridazine (Chem. Abs., 44, 5616i), 6.6 g. of formylhydrazine and 100 ml. of n-butanol are refluxed for 48 hours. The reaction mixture is cooled in an ice bath. The resulting solid is filtered, washed with petroleum ether and water and air dried giving 6-phenyl-1,2,4-triazolo[4,3-b]pyridazine as tan crystals, m.p. 138°-139° C.

Provenance & Evidence