HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → 2-(Imidazol-1-ylmethyl)-3-hydroxy-4-methylpyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | 2-Dimethylaminomethyl-3-hydroxy-4-methylpyridine | HCID 23333799 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | 2-(Imidazol-1-ylmethyl)-3-hydroxy-4-methylpyridine | HCID 23333798 | 71.2% |
Reaction Steps
The procedure described in Example 1 was then repeated except that 2-dimethylaminomethyl-3-hydroxy-4-methylpyridine (4.44 g.) and imidazole (1.82 g.) were reacted in xylene (15 ml.) to afford 2-(imidazol-1-ylmethyl)-3-hydroxy-4-methylpyridine (yield, 3.60 g.), m.p. 170°-172° C. after recrystallization from toluene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04230714 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-819b2155e7864cdfb09631673adb5f36 |
| Source note | uspto-grants-1980_10 |