Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 6-Aminonicotinamide | HCID 9500 | — |
| Reactant | tetrahydro-1-methyl-4-oxo-1H-imidazol-2-ylidene carbamic acid | HCID 136469822 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 136109368 | HCID 136109368 | 71.5% |
Reaction Steps
A mixture of 1.00 g (4.29 mM) of the phenyl carbamate 8 and 0.59 g (4.29 mM) of 6-aminonicotinamide in 4 ml of anhydrous DMF was stirred at 65° C. for 1.5 hr., cooled and poured into water. The resulting precipitate was collected, washed with acetone and air dried to give 0.85 g of the above urea as a pale yellow solid, m.p. 240°-243° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04230713 |
|---|
| Source dataset | uspto-grants-1980_10 |
|---|
| ORD ID | ord-189fb0805c4a4d208426cce85d4179e9 |
|---|
| Source note | uspto-grants-1980_10 |
|---|
