Chlorosuccinimide → HCID 23333598, compound

Participants

Reaction Steps

Methyl 5,6-dihydro-5-methyl-11-oxodibenz[b,e]azepine-2-acetate (2.0 g) was dissolved in chloroform (50 ml), and the solution was refluxed for 2 hours with the addition of N-chlorosuccinimide (1.4 g). The reaction mixture was treated in the same manner as described in Example 8 to obtain 5,6-dihydro-4-chloro-5-methyl-11-oxodibenz[b,e]azepine-2-acetic acid (1.2 g) having a melting point of 168.0°-170° C. (prismatic crystals).

Provenance & Evidence