Acetyl chloride → HCID 23333621, compound

HRID 904200Notes

Reaction equation

HRID 904200 reaction equation
C([N:8]1[CH2:14][C:13]2[CH:15]=[CH:16][CH:17]=[CH:18][C:12]=2[C:11](=[O:19])[C:10]2[CH:20]=[CH:21][CH:22]=[CH:23][C:9]1=2)C1C=CC=CC=1.[Cl-].[Al+3].[Cl-].[Cl-].[C:28](Cl)(=[O:30])[CH3:29]>C(Cl)Cl>[C:28]([C:21]1[CH:22]=[CH:23][C:9]2[NH:8][CH2:14][C:13]3[CH:15]=[CH:16][CH:17]=[CH:18][C:12]=3[C:11](=[O:19])[C:10]=2[CH:20]=1)(=[O:30])[CH3:29]

Participants

5

Reactant 3

HCID 6367Acetyl chlorideHCID 6451240Aluminum(III) ChlorideHCID 21814004HCID 21814004, compound

Product 1

HCID 23333621HCID 23333621, compoundYield 47.2%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

5,6-Dihydro-5-benzyl-11-oxodibenz[b,e]azepine (10.1 g), anhydrous aluminum chloride (16 g), acetyl chloride (8 g) and methylene chloride (100 ml) were treated in the same manner as described in Example 25 to obtain the desired compound (4 g).

Sources & evidence

ORD record
ord-074c804012c64793b9713cd9c911716c
Source dataset
uspto-grants-1980_10
Patent number
US04230703

Reaction notes

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