HCID 14698185, compound → HCID 13245269, compound

Participants

Reaction Steps

A 2.0 g sample of 7,8-didehydro-3-methoxy-17-methylmorphinan-6-one (prepared as described by SAWA et al., Tetrahedron 20: 2247 [1964]) was dissolved in 300 ml of 95% ethanol and hydrogenated at 50 psi for 4 hours using 150 mg of 10% Pd/C catalyst. The solution was filtered and evaporated to yield a crystalline residue. The product was recrystallized from ethanol to give 760 mg of product, mp 187°-188.5° C. (lit. mp 188°-189° C.).

Provenance & Evidence