反应详情

To a solution of 15 g of 2-(4-iodophenyl)-2-methyloxirane in 75 ml of toluene was added 1.5 g of powdered Molecular Sieves 4A and the mixture was heated under reflux for 4 hours. After completion of the reaction, the Molecular Sieves was removed by filtration and the filtrate was concentrated and then distilled under reduced pressure to obtain 12.5 g (83% yield) of 2-(4-iodophenyl)propionaldehyde in oily form.

1. temperaturethe mixture was heated
2. temperatureunder reflux for 4 hours
3. customAfter completion of the reaction
4. customthe Molecular Sieves was removed by filtration
5. concentrationthe filtrate was concentrated
6. distillationdistilled under reduced pressure