関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Methanesulfonyl chloride | HCID 31297 | — |
| 反応物 | 12-Hydroxydodecanenitrile | HCID 10330348 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 12-(Methanesulfonyloxy)dodecanonitrile | HCID 21163389 | — |
反応手順
A solution of 15 g. of 12-hydroxydodecanonitrile and 14 ml. of triethylamine in 320 ml. of methylene chloride is stirred at 0° C. while 5.7 ml. of methanesulfonylchloride is added dropwise. The mixture is stirred at 0° C. for 1 hour, diluted with methylene chloride and extracted with water; cold, dilute hydrochloric acid; saturated aqueous sodium bicarbonate; and brine. The solution is dried over anhydrous magnesium sulfate and eaporated to yield 12-(methanesulfonyloxy)dodecanonitrile as a yellow oil
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US04230628 |
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| 出典データセット | uspto-grants-1980_10 |
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| ORD ID | ord-e37a4953a573467f99662f7bda5b71b2 |
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| 出典メモ | uspto-grants-1980_10 |
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