HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-(15-Carboxypentadecylamino)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Ethyl 4-(15-carbomethoxypentadecylamino)benzoate | HCID 21163354 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-(15-Carboxypentadecylamino)benzoic acid | HCID 10295293 | — |
Reaction Steps
A solution of 8.8 g. of ethyl 4-(15-carbomethoxypentadecylamino)benzoate, 4.5 g. of potassium hydroxide, and 10 ml. of water in 90 ml. of ethanol is stirred at 75° for 10 hours, cooled, diluted with water, brought to pH 4 with dilute hydrochloric acid, and filtered. The solid is dried and crystallized from acetic acid to yield 4-(15-carboxypentadecylamino)benzoic acid as a white crystalline solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04230628 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-168153b1b0424573b1fb911b2e34ea8e |
| Source note | uspto-grants-1980_10 |