HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Chloroethyl)morpholine → 4-(2'-Morpholinoethoxy)-3-phenyl-coumarin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Chloroethyl)morpholine | HCID 76727 | — |
| Reactant | Coumarin, 4-hydroxy-3-phenyl- | HCID 54688870 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 4-(2'-Morpholinoethoxy)-3-phenyl-coumarin | HCID 23334050 | 80% |
Reaction Steps
By causing 100 g. (0.42 mol) of 3-phenyl-4-hydroxy-coumarin and 86.8 g. (0.55 mol) of 2-morpholino-1-chlorethane to react in the manner described in Example 1, 119 g. of a white solid are obtained. M.P. 97° C. (isopropanol), yield 80% (theoretical yield 147 g.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04230850 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-8a0a4bcb326f4019b264b54fe748457a |
| Source note | uspto-grants-1980_10 |