HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3-Chloropropyl)morpholinium chloride → 4-(3'-Morpholinopropoxy)-3-phenyl-coumarin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3-Chloropropyl)morpholinium chloride | HCID 12296283 | — |
| Reactant | Coumarin, 4-hydroxy-3-phenyl- | HCID 54688870 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 4-(3'-Morpholinopropoxy)-3-phenyl-coumarin | HCID 23334056 | 71% |
Reaction Steps
This compound is obtained by the method indicated in Example 8, from 14.3 g. (0.06 mol) of 4-hydroxy-3-phenyl-coumarin and 15.6 g. (0.078 mol) of 3-morpholino-1-chloropropane hydrochloride. 15.6 g. of a white solid are isolated. Yield 71% (theoretical yield 21.9 g.); M.P. 82° C. (isopropanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04230850 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-f52c27df0db34e649570e622c832e52b |
| Source note | uspto-grants-1980_10 |