HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Chloroethyl)morpholine → HCID 23334054, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Chloroethyl)morpholine | HCID 76727 | — |
| Reactant | 4-Hydroxy-7-methoxy-3-phenyl-2H-1-benzopyran-2-one | HCID 54705595 | — |
| Product | HCID 23334054 | HCID 23334054 | 70.8% |
Reaction Steps
This compound is prepared according to the method described in Example 8 from 24.2 g. (0.09 mol) of 3-phenyl-4-hydroxy-7-methoxy-coumarin and 17.5 g. (0.117 mol) of 2-morpholino-1-chlorethane. After recrystallisation from a mixture of diisopropyl ether and ethyl acetate (70-30), 24.3 g. of a white solid are obtained. M.P. 95°-96° C.; yield 70.8% (theoretical yield 34.3 g.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04230850 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-6117239409524c34892393389683e230 |
| Source note | uspto-grants-1980_10 |