HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Chloroethyl)morpholine → 3-Benzyl-4-(2'-morpholinoethoxy)-coumarin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Chloroethyl)morpholine | HCID 76727 | — |
| Reactant | 4-Hydroxy-3-benzylcoumarin | HCID 54686112 | — |
| Product | 3-Benzyl-4-(2'-morpholinoethoxy)-coumarin | HCID 23334071 | 88.5% |
Reaction Steps
Prepared as indicated in Example 8, from 13.7 g. (0.54 mol) of 3-benzyl-4-hydroxy-coumarin and 10.6 g. (0.071 mol) of 2-morpholino-1-chlorethane. After evaporation of the chloroform, there are obtained 17 g. of an oil which cannot be crystallised. Yield 88.5% (theoretical yield 19.2 g.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04230850 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-7beff3d84ec34edb993410793283d6bc |
| Source note | uspto-grants-1980_10 |