HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3-Chloropropyl)morpholine → 4-(3'-Morpholinopropoxy)-3-phenyl-5,6,7,8-tetrahydrocoumarin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3-Chloropropyl)morpholine | HCID 95834 | — |
| Reactant | 4-Hydroxy-3-phenyl-5,6,7,8-tetrahydrocoumarin | HCID 54721330 | — |
| Product | 4-(3'-Morpholinopropoxy)-3-phenyl-5,6,7,8-tetrahydrocoumarin | HCID 23334060 | 45.7% |
Reaction Steps
Obtained by causing the reaction, as indicated in Example 14, Stage B, of 14.5 g. (0.06 mol) of 4-hydroxy-3-phenyl-5,6,7,8-tetrahydrocoumarin with 15.6 g. (0.078 mol) of 3-morpholino-1-chloropropane. 10.1 g. of a paste which cannot be crystallised are isolated. Yield 45.7% (theoretical yield 22.1 g.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04230850 |
| Source dataset | uspto-grants-1980_10 |
| ORD ID | ord-26a9fd29fafa4de48fed25067ab59183 |
| Source note | uspto-grants-1980_10 |