HCID 13034082, compound → HCID 23334082, compound

HRID 904323Notes

Reaction equation

HRID 904323 reaction equation
[OH:1][C:2]1[C:11]2[CH2:10][CH2:9][CH2:8][CH2:7][C:6]=2[O:5][C:4](=[O:12])[C:3]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[N:19]1([CH2:25][CH:26]([CH3:29])[CH2:27]Cl)[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]1>>[N:19]1([CH2:25][CH:26]([CH3:29])[CH2:27][O:1][C:2]2[C:11]3[CH2:10][CH2:9][CH2:8][CH2:7][C:6]=3[O:5][C:4](=[O:12])[C:3]=2[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]1

Participants

3

Reactant 2

HCID 13034082HCID 13034082, compoundHCID 547213304-Hydroxy-3-phenyl-5,6,7,8-tetrahydrocoumarin

Product 1

HCID 23334082HCID 23334082, compoundYield 82%

Procedure

Prepared according to the method of Example 13 by alkylation of 4-hydroxy-3-phenyl-5,6,7,8-tetrahydrocoumarin with 3-piperidino-2-methyl-1-chloropropane. A thick oil is obtained which cannot be crystallised. Yield 82%.

Workup

  1. customPrepared
  2. customA thick oil is obtained which
  3. customcannot be crystallised

Sources & evidence

ORD record
ord-8f4a0ed1e3ed4c51abee47896274618b
Source dataset
uspto-grants-1980_10
Patent number
US04230850

Reaction notes

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