3-Morpholino-1-chlorobutane → 4-(3'-Morpholinobutoxy)-3-phenyl-coumarin

HRID 904324Notes

Reaction equation

HRID 904324 reaction equation
[OH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[O:5][C:4](=[O:12])[C:3]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[O:19]1[CH2:24][CH2:23][N:22]([CH:25]([CH3:29])[CH2:26][CH2:27]Cl)[CH2:21][CH2:20]1>>[O:19]1[CH2:24][CH2:23][N:22]([CH:25]([CH3:29])[CH2:26][CH2:27][O:1][C:2]2[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[O:5][C:4](=[O:12])[C:3]=2[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH2:21][CH2:20]1

Participants

3

Reactant 2

HCID 233340813-Morpholino-1-chlorobutaneHCID 54688870Coumarin, 4-hydroxy-3-phenyl-

Product 1

HCID 233340724-(3'-Morpholinobutoxy)-3-phenyl-coumarinYield 72.5%

Procedure

Prepared according to the method of Example 8 from 4-hydroxy-3-phenyl-coumarin and 3-morpholino-1-chlorobutane. An oil is obtained which cannot be crystallised. Yield 72.5%.

Workup

  1. customPrepared
  2. customAn oil is obtained which
  3. customcannot be crystallised

Sources & evidence

ORD record
ord-2696e429f3844f45b03cb76a68904035
Source dataset
uspto-grants-1980_10
Patent number
US04230850

Reaction notes

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