HCID 23334044, compound → HCID 23334076, compound

HRID 904326Notes

Reaction equation

HRID 904326 reaction equation
[OH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[O:5][C:4](=[O:12])[C:3]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[O:19]1[CH2:24][CH2:23][N:22]([CH2:25][C:26]([CH3:30])([CH3:29])[CH2:27]Cl)[CH2:21][CH2:20]1>>[O:19]1[CH2:24][CH2:23][N:22]([CH2:25][C:26]([CH3:30])([CH3:29])[CH2:27][O:1][C:2]2[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[O:5][C:4](=[O:12])[C:3]=2[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH2:21][CH2:20]1

Participants

3

Reactant 2

HCID 23334044HCID 23334044, compoundHCID 54688870Coumarin, 4-hydroxy-3-phenyl-

Product 1

HCID 23334076HCID 23334076, compoundYield 87.2%

Procedure

Prepared according to the method of Example 8 from 4-hydroxy-3-phenyl-coumarin and 3-morpholino-2,2-dimethyl-1-chloropropane. By recrystallisation from ethanol, a solid melting at 167° C. is obtained. Yield 87.2%.

Workup

  1. customPrepared
  2. customBy recrystallisation from ethanol

Sources & evidence

ORD record
ord-57c0f860eac542ae872f0887036b60cc
Source dataset
uspto-grants-1980_10
Patent number
US04230850

Reaction notes

Loading…