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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 904327Generated: October 30, 2026

4-(3-Chloro-2-methylpropyl)morpholine → 8-Chloro-4-(3'-morpholino-2'-methylpropoxy)-3-phenylcoumarin

https://huagongshe.com/reaction/904327

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(3-Chloro-2-methylpropyl)morpholineHCID 23334047—
Reactant8-Chloro-4-hydroxy-3-phenylcoumarinHCID 54721336—
Product8-Chloro-4-(3'-morpholino-2'-methylpropoxy)-3-phenylcoumarinHCID 2333407769%

Reaction Steps

Prepared by alkylation of 8-chloro-4-hydroxy-3-phenylcoumarin by 3-morpholino-2-methyl-1-chloropropane, in accordance with the method of Example 8. By recrystallisation from ethanol, a solid melting at 120°-122° C. is obtained. Yield 69%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04230850
Source datasetuspto-grants-1980_10
ORD IDord-3749633a03d44683b7828f1ff868a1a7
Source noteuspto-grants-1980_10