HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → {(2-Chloro-6-fluoro-phenyl)-[2-(4-chloro-phenyl)-1H-indol-3-yl]-methyl}-dimethyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 2-Chloro-6-fluorobenzaldehyde | HCID 67847 | — |
| Reactant | 2-(4-Chlorophenyl)-1H-indole | HCID 220463 | — |
| Reactant | (2-Chloro-6-fluoro-benzylidene)-dimethylammonium chloride | HCID 21985312 | — |
| Product | {(2-Chloro-6-fluoro-phenyl)-[2-(4-chloro-phenyl)-1H-indol-3-yl]-methyl}-dimethyl-amine | HCID 21985282 | — |
Reaction Steps
The preparation was carried out in accordance with general synthesis instructions 4 from 2-(4-chlorophenyl)-indole and (2-chloro-6-fluoro-benzylidene)-dimethyl-ammonium chloride, which had been prepared in accordance with example 24 from 2-chloro-6-fluoro-benzaldehyde and dimethylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07091220B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-481423226194464382ed5e4c678c6fee |
| Source note | uspto-grants-2006_08 |