Ethyl orthoformate → HCID 178423910, compound

HRID 904639Notes

Reaction equation

HRID 904639 reaction equation
[NH2:1][C:2]1[C:15]([CH3:16])=[CH:14][CH:13]=[CH:12][C:3]=1[C:4]([NH:6][C:7]1[NH:11][N:10]=[N:9][N:8]=1)=[O:5].[CH2:17](OC(OCC)OCC)C>>[CH3:16][C:15]1[CH:14]=[CH:13][CH:12]=[C:3]2[C:2]=1[N:1]=[CH:17][N:6]([C:7]1[NH:11][N:10]=[N:9][N:8]=1)[C:4]2=[O:5]

Participants

3

Reactant 2

HCID 31214Ethyl orthoformateHCID 178425299HCID 178425299, compound

Product 1

HCID 178423910HCID 178423910, compound

Procedure

Reaction of 2-amino-3-methyl-N-(1H-tetrazol-5-yl)benzamide with triethoxymethane gave 8-methyl-3-(1H-tetrazol-5-yl)-4(3H)-quinazolinone melting at about 268° C. (dec) after recrystallization from dimethylformamide.

Sources & evidence

ORD record
ord-d1da44f50dda447db8285c03496a037e
Source dataset
uspto-grants-1983_12
Patent number
US04419357

Reaction notes

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