Thionyl Chloride → HCID 20478449, compound

Participants

Reaction Steps

The product of step (a) (1.35 g; 3.9 mmole) suspended in dichloroethane was treated with thionyl chloride (0.9 g; 7.5 mmole) and dimethylformamide (4 drops). The mixture was heated under reflux for 6 hrs adding more thionyl chloride (0.2 ml) after 3 hrs. The mixture was evaporated to dryness and triturated with ether to give a buff solid (1.35 g; 96%), mp 193° shown to be the title compound by its NMR and mass spectrum.

Provenance & Evidence