Ammonia → HCID 13282658, compound

Participants

Reaction Steps

Liquid anhydrous ammonia (10 ml) was added to a stirred suspension of the product from Example 13 in 350 ml dry diethyl ether at 0°-5° C. over a period of 20 minutes. The reaction mixture was stirred at 0°-5° C. for 30 minutes and was allowed to warm to room temperature over a two hour period. The solids were filtered and washed with diethyl ether. Concentration of the filtrate in vacuo gave a yellow solid which was washed with water, 1-chlorobutane, and then dried under vacuum to yield 17 g of 1-(2-nitrophenyl)ethanesulfonamide as a pale yellow solid, m.p. 107°-109° C.

Provenance & Evidence