Acetic Anhydride → HCID 13435388, compound

HRID 904819Notes

Reaction equation

HRID 904819 reaction equation
[N:1](=[C:3]1[CH2:12][CH2:11][C:10]2[C:5](=[CH:6][C:7]([O:13][CH3:14])=[CH:8][CH:9]=2)[C:4]1=[O:15])O.[C:16](OC(=O)C)(=[O:18])[CH3:17]>[Pd]>[C:16]([NH:1][CH:3]1[CH2:12][CH2:11][C:10]2[C:5](=[CH:6][C:7]([O:13][CH3:14])=[CH:8][CH:9]=2)[C:4]1=[O:15])(=[O:18])[CH3:17]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 73667394HCID 73667394, compound

Product 1

HCID 13435388HCID 13435388, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

A mixture of 2-oximino-7-methoxy-3,4-dihydronaphthalen-1(2H)-one (8.7 gm, 0.04 m), palladium on carbon (10%, 1 gm) tetrahydrofuran (150 ml) and acetic anhydride (25 ml) was hydrogenated on a Parr apparatus for 3 hours. The catalyst was filtered, and the solvents were removed under reduced pressure to yield the product as an oil, which was used in the next step without further purification.

Workup

  1. filtrationThe catalyst was filtered
  2. customthe solvents were removed under reduced pressure

Sources & evidence

ORD record
ord-cd33c48e43c74e399e20dc0c16a9f271
Source dataset
uspto-grants-1983_12
Patent number
US04420480

Reaction notes

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