反应详情

温度

100 °C

In a round bottomed flask equipped with a condenser 24.0 g of 2-amino-4-chloro-5-sulfamyl-aniline and 7.0 g of formic acid is refluxed at 100° C. for two hours. Concentrate under vacuum. Dissolve in hot methanol, stir, cool and filter off the solid wt.=11.0 gm. m.p. 243.8° C.

1. concentrationConcentrate under vacuum
2. dissolutionDissolve in hot methanol
3. temperaturecool
4. filtrationfilter off the solid wt.=11.0 gm