Acetic Acid → HCID 13276358, compound

Participants

Reaction Steps

A solution of 11β-(acetyloxy)-17,17-bis-(ethylthio)-9-fluoro-16α-hydroxyandrosta-1,4-dien-3-one (100 mg, 0.207 mmole) in a mixture of dry dimethylsulfoxide (2.0 ml), acetic anhydride (0.7 ml) and acetic acid (0.1 ml) was left standing at room temperature for 18 hours. The mixture was then added to water and was extracted with chloroform. The chloroform solution was washed with water, dried (MgSO4) and evaporated to afford the title compound (94 mg) as a solid.

Provenance & Evidence