反应详情

To a solution of N,N-dimethyl-N'-(3-cyano-4,6-dimethyl-2-pyridyl)-1,2-diaminoethane (13.5 g, 62 mmol) in dry benzene (150 ml) is added methyl chloroformate (7.1 ml, 92 mmol) and then the resulting mixture is refluxed for 11/2 hours. This mixture is evaporated to dryness and the residue dissolved in water, washed with methylene chloride, made basic with sodium carbonate and the product extracted into methylene chloride. Upon evaporation of the solvent there is obtained 16.6 g of oily title B product.

1. temperaturethe resulting mixture is refluxed for 11/2 hours
2. customThis mixture is evaporated to dryness
3. dissolutionthe residue dissolved in water
4. washwashed with methylene chloride
5. extractionthe product extracted into methylene chloride
6. customUpon evaporation of the solvent there
7. customis obtained 16.6 g of oily title B product