反应详情

Seventy grams (0.63 mole) maleic anhydride is dissolved in 300 mls n-butanol containing one gram p-toluene sulfonic acid. The solution is refluxed for 16 hours during which the water formed is removed with a Dean Stark trap. The excess butanol is then distilled in vacuo to give a residue of 200 g of dibutyl maleate (structure verified by NMR analysis).

1. customformed
2. customis removed with a Dean Stark trap
3. distillationThe excess butanol is then distilled in vacuo