N-Carbobenzoxy-L-valine → HCID 131713305, compound

Participants

Reaction Conditions

Reaction Steps

6.27 g (25 mmoles) of Z-Val-OH and 7.52 g (25 mmoles) of H-Tyr(But)-NH-C2H5.HCl are subjected to a condensation reaction analogously to Example 30 C. After being precipitated by means of water, the substance is dissolved in 70 ml of 95 percent strength alcohol and the solution is filtered hot and cooled (3 hours at 4° C.). The precipitate is filtered off. Yield 9.01 g (72.5%), melting point 181°, [α]D23 =-39.8° (c=1, dimethylformamide).

Provenance & Evidence