Hydrochloric Acid → Phosphonic acid, [2-nitro-5-[2-nitro-4-(trifluoromethyl)phenoxy]phenyl]-

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Reaction Steps

A mixture of 1.85 g of the 2-nitro-5-(2'-nitro-4'-trifluoromethylphenoxy)-phenylphosphonic acid diethyl ester obtained in Example 1, in 20 ml of ethanol, and 40 ml of 20% hydrochloric acid, is refluxed for 24 hours and then evaporated to dryness, affording as residue the monohydrate of the corresponding free phosphonic acid in the form of yellowish brown crystals in quantitative yield. Melting point: 175°-180° C.

Provenance & Evidence