HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 905009Generated: October 29, 2026
Acetyl chloride → 3,3-Difluorooxolane-2,5-dione
https://huagongshe.com/reaction/905009
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 2,2-Difluorosuccinic acid | HCID 69581 | — |
| Product | 3,3-Difluorooxolane-2,5-dione | HCID 13189243 | — |
Reaction Steps
To a solution of 10.8 mL of acetic anhydride and 10.8 mL of acetyl chloride at 0° C. was added 10.80 g (0.070 mol) of 2,2-difluorosuccinic acid in several portions. The mixture was heated for 1 hr at 50° C. and cooled. The reaction was concentrated under reduced pressure to yield 2,2-difluorosuccinic anhydride. NMR (CDCl3) δ3.56 ppm (triplet, 2, J=15 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04421690 |
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| Source dataset | uspto-grants-1983_12 |
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| ORD ID | ord-e426336fe26543fc847359a25070b833 |
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| Source note | uspto-grants-1983_12 |
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