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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 905030Generated: October 30, 2026

Hydrochloric Acid → HCID 13231126, compound

https://huagongshe.com/reaction/905030

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPotassium HydroxideHCID 14797—
ReactantHCID 13231125HCID 13231125—
SolventEthanolHCID 702—
SolventWaterHCID 962—
ProductHCID 13231126HCID 13231126—

Reaction Steps

21.4 g of the resulting 4-(4-benzoylbutyl)-1-(ethoxycarbonylamino)piperazine was dissolved in 180 ml of ethanol, and a solution of 36.2 g of potassium hydroxide in 36 ml of water was added. The mixture was heated under reflux for 3 hours. The reaction mixture was cooled, and 136 ml of 4N hydrochloric acid was added to form a 4-(4-benzoylbutyl)-1-aminopiperazine solution.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04421754
Source datasetuspto-grants-1983_12
ORD IDord-0a67049f95364f8fb22ad497ed8cf721
Source noteuspto-grants-1983_12