Dimethyl N-cyanodithioiminocarbonate → HCID 13267628, compound

HRID 905036Notes

Reaction equation

HRID 905036 reaction equation
[F:1][C:2]1[CH:14]=[CH:13][C:5]([CH2:6][N:7]2[CH2:12][CH2:11][NH:10][CH2:9][CH2:8]2)=[CH:4][CH:3]=1.[CH3:15][S:16][C:17](SC)=[N:18][C:19]#[N:20]>C(O)C>[C:19]([N:18]=[C:17]([N:10]1[CH2:11][CH2:12][N:7]([CH2:6][C:5]2[CH:13]=[CH:14][C:2]([F:1])=[CH:3][CH:4]=2)[CH2:8][CH2:9]1)[S:16][CH3:15])#[N:20]

Participants

4

Reactant 2

HCID 66289Dimethyl N-cyanodithioiminocarbonateHCID 7965631-(4-Fluorobenzyl)piperazine

Product 1

HCID 13267628HCID 13267628, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

A 28.7 g. (0.1 mole) portion of N-(p-fluorobenzyl)piperazine was dissolved in 25 ml. of ethanol and then added dropwise over 30 minutes to a stirred solution of 14.6 g. (0.1 mole) of dimethyl cyanodithioiminocarbonate in 200 ml. of ethanol. The mixture was refluxed for 6 hours, the evolved gas being led through a sodium hypochlorite trap. The mixture was then evaporated to a syrup.

Workup

  1. temperatureThe mixture was refluxed for 6 hours
  2. customthe evolved gas being led through a sodium hypochlorite trap
  3. customThe mixture was then evaporated to a syrup

Sources & evidence

ORD record
ord-302cabadfbd147c7bb4dc1b9459f5bff
Source dataset
uspto-grants-1983_12
Patent number
US04421753

Reaction notes

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