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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 905077Generated: October 30, 2026

Imidazole → HCID 13079736, compound

https://huagongshe.com/reaction/905077

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazoleHCID 795—
ReactantSodium IodideHCID 5238—
ReactantHCID 54561442HCID 54561442—
SolventDimethylformamideHCID 6228—
ProductHCID 13079736HCID 13079736—

Reaction Steps

130 mg of the isomer of lesser polarity of trans-6-(4-chlorobenzylthiomethyl)-2-[2-bromo-1-(2,4-dichlorophenyl)ethoxy]tetrahydropyran, 67.5 mg of imidazole and 74 mg of sodium iodide were reacted in dimethylformamide at 130° C. for 9 hours and then treated and the product purified essentially as described in Example 34(b)(i), to give 60 mg of the title compound in the form of a colourless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04421758
Source datasetuspto-grants-1983_12
ORD IDord-028f32322ed44a558c60e2dad351637f
Source noteuspto-grants-1983_12