1-Octanol → HCID 53635237, compound

Participants

Reaction Steps

A suspension of 2.1 g (50 millimols) of sodium hydride (in oil) is added in small amounts to 6.5 g (50 millimols) of octan-1-ol in 100 ml of toluene, whilst stirring. When the evolution of hydrogen has ended, 16.6 g (50 millimols) of 3-(p-bromomethylbenzylidene)-camphor are added in portions, and the mixture is then heated under reflux for 3 hours. After adding water, the toluene phase is decanted, dried and concentrated to dryness. The residual syrup is distilled under reduced pressure. 8.8 g of a yellow liquid, which boils at 240° under a pressure of 0.1 mm Hg, are thus collected.

Provenance & Evidence