HuagongsheHuagongshe Chemistry Print Report · For research reference only
Fuming sulfuric acid → Sulfuric Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Fuming sulfuric acid | HCID 24681 | — |
| Reactant | 7-Chloro-2,3-dihydro-4-quinolone | HCID 88974 | — |
| Reactant | 3-((3-Chlorophenyl)amino)propanoic acid | HCID 12470919 | — |
| Product | Sulfuric Acid | HCID 1118 | — |
| Product | 7-Chloro-2,3-dihydro-4-quinolone | HCID 88974 | — |
Reaction Steps
A process for the preparation of 7-chloro-1,2,3,4-tetrahydroquinolin-4-one which comprises cyclising 3-m-chloroanilinopropionic acid by means of an oleum, then desulphonating the intermediate aromatic sulphonic acids of the formula: ##STR3## (wherein n is 1 or 2) by means of dilute sulphuric acid, and then isolating the 7-chloro-1,2,3,4-tetrahydroquinolin-4-one obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04421918 |
| Source dataset | uspto-grants-1983_12 |
| ORD ID | ord-a2414c36dbfc4cbcb7a2071797154c4e |
| Source note | uspto-grants-1983_12 |